Ethylcellulose-Based Matrix-Type Microspheres: Influence of Plasticizer RATIO as Pore-Forming Agent
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چکیده
منابع مشابه
STUDY OF THE WIDELY USED ETHYLCELLULOSE POLYMER AS FILM FORMING AND MATRIX FORMER AGENT Ph.D. Thesis
The aim of our research was to investigate theeffect of the length of the polymer chain and the concen-tration of triethyl citrate used as a plasticizer on the thermalstability of the film structure in the case of two ethyl cel-lulose films (EC 10 and EC 45) used for preparing MRdosage forms. The influence of storage time was studied bymonitoring the changes in the therm...
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In the long-term management of ulcerative colitis patients, repeat dosing maybe required. Since 5-ASA is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. The aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-ASA deliver...
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Microspheres are one of the novel drug delivery system and are formulated conveniently to obtain prolonged or controlled drug delivery to enhance the bioavailability and target drug to the specific sites. Ritonavir loaded ethylcellulose buoyant microspheres were formulated using ethylcellulose as rate retarding material. Buoyant microspheres were formulated by emulsion solvent diffusion method....
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2011
ISSN: 1530-9932
DOI: 10.1208/s12249-011-9680-4